New study offers hope for extending ovarian healthspan and function
A woman's ovaries are like a factory where eggs grow and produce hormones that regulate everything from menstruation and pregnancy to bone density and mood.
View ArticleIn silico docking of clinically approved drugs against the SARS-CoV-2...
Announcing a new article publication for BIO Integration journal. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in China in December 2019, rapidly spread worldwide,...
View ArticleBlocking Piezo2 may offer a new therapeutic approach for pulmonary fibrotic...
Researchers have found a potential new way to slow the progression of lung fibrosis and other fibrotic diseases by inhibiting the expression or function of Piezo2, a receptor that senses mechanical...
View ArticleAdvancing pulmonary fibrosis treatment through targeted drug delivery
Announcing a new article publication for BIO Integration journal. Pulmonary fibrosis (PF) is a progressive interstitial lung disease characterized by excessive extracellular matrix deposition and...
View ArticleGlobal clinical trial tests two anti-inflammatory drugs for long COVID
Spanning four continents and enrolling hundreds of people, a new clinical trial will test the effectiveness of two anti-inflammatory medicines as potential treatments for long COVID, scientists from...
View ArticleAI-designed drug shows early promise for lung fibrosis patients in clinical...
Researchers report that rentosertib, an AI-discovered TNIK inhibitor, showed promising safety and potential to improve lung function in patients with idiopathic pulmonary fibrosis in a 12-week phase 2a...
View ArticleQureight's synthetic study arms validate clinical efficacy in pioneering rare...
Qureight, a deep-learning analytics company accelerating drug development through AI-powered data curation, today announced that its digitally-twinned synthetic control arm has been used in a...
View ArticleTargeting TGF-β signaling as a strategy to treat liver fibrosis
Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health burden due to its potential progression to cirrhosis and hepatocellular...
View ArticleNew study solves lung transplant rejection mystery
More than 50% of lung-transplant recipients experience a rejection of their new lung within five years of receiving it, yet the reason why this is such a prevalent complication has remained a medical...
View ArticleMachine learning identifies natural compound to treat lung disease
A new study published in Engineering has combined machine learning (ML) and experimental validation to identify dihydromyricetin (DHM), a natural flavonoid, as a potent inhibitor of the TGF-β/ALK5...
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